The story centers around a poor teenage girl Dong Shān Cài (Barbie Shu), who at the insistence of her parents goes to a university for rich people. The university is dominated by Dào Míng Sì (Jerry Yan), Huā Zé Lèi (Vic Zhou), Měi Zuò (Vanness Wu) and Xī Mén (Ken Chu)—four rich, handsome but arrogant students collectively known as the ‘F4’, short for ‘Flower 4’. They are heirs to four rich and influential families in Taiwan. They terrorize the school by handing out red cards to those they do not like, which allows other students to bully the victims until they leave the school.
After one of Shān Cài’s friends receives the wrath of the F4’s leader, Dào Míng Sì, she stands up to and berates him, which in turn results in a red card of her own. Shān Cài hates the arrogant and rude Dào Míng Sì. Her persistence in standing up for what is right gradually gains the F4’s respect and Dào Míng Sì starts to fall for her. Shān Cài is attracted to the silent Huā Zé Lèi in the beginning. But Dào Míng Sì’s constant yet annoying efforts has her question her feelings for both Huā Zé Lèi and Dào Míng Sì.
Later in the series, Dào Míng Sì’s mother comes to Taiwan. She instantly dislikes Shān Cài because of her poor background. Both Dào Míng Sì and Shān Cài face hurdles his mother throws their way to separate them. Though Shān Cài does not profess her love for him yet, Dào Míng Sì remains determined. The series show the journey of Dào Míng Sì and Shān Cài’s feelings for one another.